JAK2 and neoplasm: In non-malignant cells, the expression of IL-6 (P = 0.005), gp-130 (P < 0.001), CRP (P = 0.020), and JAK2 (P = 0.002) was lower in tumor tissues compared with normal tissues (Figure 6B), while expression of IL6R and STAT3 showed no significant difference in malignant cells (P > 0.05, Figure 6B).