STAT3 and neoplasm: In SA region, the expression of CRP (P = 0.048), gp-130 (P < 0.001), JAK2 (P = 0.004), and IL-6 (P = 0.001) was lower in tumor tissues compared with normal tissues, while the expression of IL-6R (P = 0.191) and STAT3 (P = 0.960) was comparable (Supplementary Figure 1).