In tumor tissues, there was a moderate correlation between IL-6 and STAT3 (r = 0.449, P < 0.001), whereas a weak correction between IL-6 and gp130 (r= 0.314, P = 0.002), as well as JAK2 (r = 0.230, P = 0.028). This evidence concerns the gene STAT3 and neoplasm.