Among immune system diseases like osteoarthritis (20) and rheumatoid arthritis (21), septicemia (22), atherosclerosis, osteoporosis (23), diabetes (18), atopic dermatitis (24), epithelial ovarian cancer (25), and obesity (26), LECT2 can activate and recruit immune cells to regulate inflammatory responses and immune responses (9). Here, LECT2 is linked to osteoarthritis.