HMGB1 and necrotizing enterocolitis: Mouse models (utilizing formula gavage/hypoxia)• Increased serum HMGB1 in murine NEC (19)• Increased intestinal HMGB1 expression in murine NEC (19–21)Mouse models (utilizing formula and enteric bacteria gavage/hypoxia)• Increased serum HMGB1 in murine NEC (22)Rat models (utilizing formula gavage/hypoxia)• Increased expression of HMGB1 in ileal mucosa (23, 24)Rat models (utilizing formula gavage/LPS/hypoxia)• Increased intestinal expression of HMGB1 (25, 26)