Expression of other TLRs was decreased in jejunal and ileal tissue from NEC pup models, including TLR1 (up to 58% decrease), TLR3 (42% decrease), TLR5 (74% decrease), TLR6 (93% decrease), TLR9 (70% decrease), TLR11 (94% decrease), and TLR12 (92% decrease) (4). The gene discussed is TLR9; the disease is necrotizing enterocolitis.