65 According to the Catalogue of Somatic Mutations in Cancer (COSMIC) data set, approximately 30% of PTEN alterations in cervical cancer patients are related to gene under expression.66 Loures and co-authors demonstrated that PTEN expression intensity was lower in SCC patients compared to control patients (benign cervix) and was not associated with tumour expression of p53.67 This evidence concerns the gene PTEN and cervical cancer.