We also obtained immunohistochemical staining results of GAMT, ORC1, CNGB3 and SERPINE1 in normal gastric tissues and gastric cancer tissues from the HPA database showed that GAMT was decreased in IHC staining in gastric cancer tissues, whereas ORC1, CNGB3 and SERPINE1 were all increased in IHC staining in tumor tissues (Fig. 2C). Here, ORC1 is linked to gastric cancer.