Pan-cancer survival analysis showed that ZNF281 expression was strongly associated with the prognosis of CESE (Cervical squamous cell), ESCA, KIRP (Kidney renal papillary cell carcinoma), LUAD, PAAD (Pancreatic adenocarcinoma), SARC (Sarcoma), STAD and UCEC (Uterine Corpus Endometrial Carcinoma) (Fig. 3A). The gene discussed is ZNF281; the disease is pancreatic adenocarcinoma.