The Nephroseq database (http://www.nephroseq.org) [25] showed that EHHADH mRNA expression was downregulated in the tubules of patients with DN (Fig. S1D); the estimated glomerular filtration rate (eGFR) level of patients with DN was significantly correlated with the expression levels of EHHADH in those patients (Fig. S1E). The gene discussed is EHHADH; the disease is liver dysplastic nodule.