TMPRSS2 and infection: Human annotation of infection was compared to DVICE for a total of 3646 images (including 627 infected images) of A549-ACE2, Huh7-ACE2, or VeroE6-TMPRSS2 cells inoculated with serial dilutions of saliva spiked with SARS-CoV-2 BA.1, where DVICE achieved an AUROC of 0.918 ± 0.020.