The fact that all four genes drop in expression in NF2 mutant vestibular schwannomas in patients, as they do upon loss of NF2 in the sural-nerve derived ipn02.3 2λ Schwann cell line that we use for most of our experiments here, suggests that this biology is conserved in Schwann cells from different locations of the body. The gene discussed is NF2; the disease is Vestibular schwannoma.