HNF1A and hepatocellular carcinoma: Nude mice were subcutaneously transplanted with HCC cells infected with TRIM8 lentivirus or control lentivirus, and received intratumoral injections of adenovirus expressing GFP (Ad-GFP), HNF1α (Ad-HNF1α) or HNF1α-K197R (Ad-HNF1α-K197R).