Our results indicate that SNHG1 specifically induces BC invasion and MMP-2 expression by increasing its transcription and mRNA expression [57] and that PTEN upregulation is mediated by its degradation due to USP8 reduction and is responsible for SNHG1-mediated promotion of BMIBC cell anchorage-independent growth [53]. This evidence concerns the gene SNHG1 and breast cancer.