The increased non-HDL-apoCIII in association with large and medium TRL particles supports the idea that TRL lipolysis and clearance are impaired in SZ, and is consistent with Boiko et al. who showed that serum apoCIII levels were increased in patients with SZ in contrast to healthy individuals, and more pronounced in patients with metabolic syndrome (48). This evidence concerns the gene APOC3 and metabolic syndrome.