TP53 and breast carcinoma: The mean age of breast cancer onset in TP53 mutation carriers tended to be lower than that in BRCA mutation carriers and non-carriers (who did not carry BRCA or TP53 mutations) (mean age [range] in years: 32.5 [27–37] vs. 40.7 [22–60] vs. 45.6 [22–81], respectively).