In addition, in a nude mouse xenograft model, DANCR knockdown decreased the number of metastatic lesions formed by CW22Rv1 cells; within C4-2B and CW22RV1 PC cells, DANCR and EZH2 collaborate to hinder TIMP2/3 expression by epigenetically silencing their promoters, thereby promoting tumour metastasis [75]. Here, DANCR is linked to neoplasm.