In a hepatocellular carcinoma (HCC) study, researchers demonstrated that CSPG4P12, combining 5 other genes (BX537318.1, TMEM147, AC015908.3, CEBPZOS, and SRD5A3), served as the signature for prognostic evaluation of HCC [36]. The gene discussed is SRD5A3; the disease is hepatocellular carcinoma.