S100A6 exists in various mammalian tissues and cells and is closely related to many neoplastic diseases, such as lung cancer (Wang et al. 2021b), colorectal cancer (Wang et al. 2017), pancreatic cancer (Zihao et al. 2013), melanoma (Mitamura et al. 2014), and liver cancer (Song et al. 2020). The gene discussed is S100A6; the disease is neoplasm.