The expression of steroid-acute regulatory protein (StAR), low-density lipoprotein receptor (LDL-R), cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc), and cytochrome P450 17α-hydroxysterol dehydrogenase (P450-17α) was reduced, indicating TPHP-induced oxidative stress and endocrine disorders in mice46. The gene discussed is STAR; the disease is endocrine system disorder.