We further analysed the correlation between CXCL12, CD44v6, HIF1A, TGFBR2 and KRT7 expression in metastatic tumor tissues & exosomes with sex, age, habit, Tumor Differentiation grade, TNM stage, EGFR mutation status, AE1, Chromogranin, CDX2, CEA, CK20, TTF-1 & CK7. The gene discussed is TTF1; the disease is neoplasm.