MAPT and supranuclear palsy, progressive, 1: The lack of displacement of [3H]OXD-2314 binding to tau filaments by PI-2620, florzolotau, Tauvid and MK-6240 in AD, PSP, CBD and PiD tissues suggests that OXD-2314 binds to a different high-affinity site on tau aggregates that is not specific to a particular isoform of tau or specific to a particular pathological expression of tau.