Competition binding assays of [3H]OXD-2314 against unlabeled OXD-2115, PI-2620, florzolotau, Tauvid, MK-6240, OXD-2115 as well as unlabeled OXD-2314 in AD, PSP, CBD and PiD tissue were carried out to establish their inhibition constant (Ki) values (Table 4). This evidence concerns the gene MTA2 and Alzheimer disease.