In addition, our results also showed that scoliosis is significantly associated with the levels of T-cell surface glycoprotein CD6 isoform, hepatocyte growth factor, interleukin-18, and tumor necrosis factor ligand superfamily member 14 (Supplementary Table S2, Supplemental Digital Content, http://links.lww.com/MD/M879). The gene discussed is IL18; the disease is scoliosis.