In contrast, levels of interleukin-13 (OR = 0.808, 95% CI = 0.659−0.991, P = .041), osteoprotegerin (OR = 0.810, 95% CI = 0.685–0.957, P = .013), and tumor necrosis factor receptor superfamily member 9 (OR = 0.832, 95% CI = 0.723–0.959, P = .011) were negatively correlated with scoliosis, suggesting that the genetic prediction of these 3 IFs was related to a reduced risk of scoliosis. The gene discussed is IL13; the disease is scoliosis.