CDCA1 is a cancer assessment antigen, and its upregulation is a common and important characteristic of cancer cell growth and survival.[13] CDCA2 expression is significantly correlated with the expression of components related to cell cycle phase transition, and CDCA2 overexpression plays a significant role in tumorigenesis.[14] By stimulating certain proteins, cell mitosis and some physiological and pathological processes are regulated by CDCA3. Here, NUF2 is linked to cancer.