7 cases of AML defined by differentiation (AML-DBD), 1 case of myelodysplastic neoplasm with low blasts and SF3B1 mutation (MDS-SF3B1), 7 cases of MDS with low blasts (MDS-LB), 14 cases of MDS with increased blasts-1 (MDS-IB1), 3 cases of MDS with biallelic TP53 inactivation (MDS-biTP53), 2 cases of MDS-IB2, 2 cases of CML, 10 cases of PV, 13 cases of ET, 9 cases of PMF, 1 case of CEL, 1 case of MPN-NOS, 5 cases of CMML, and 2 cases of MDS/MPN with thrombocytosis and SF3B1 mutation (MDS/MPN-SF3B1-T). The gene discussed is SF3B1; the disease is essential thrombocythemia.