RASA1 and brain stem glioma: The RASA1 c.2656 C > T (p.(Pro886Ser) variant was found in N75, a ten years’ old patient, with an early diagnosis (at 8 months of age), based on the presence of CALs and lentigo, who, at 4 years of age, developed a brainstem glioma that remained radiologically stable and clinically asymptomatic.