Mouse models of liver fibrosis using a methionine and choline-deficient diet, high-fructose, high-palmitate, and high-cholesterol (FPC) diets, or repetitive intraperitoneal injections of CCl4 all show increased YAP/TAZ activity accompanied by fibrous scarring and ECM accumulation (Wang et al. 2016; Salloum et al. 2021; Du et al. 2023). Here, YAP1 is linked to Hepatic fibrosis.