The median values for ET-1 in each group were as follows: 0.17 × 10− 3 (0.07 × 10− 3 – 0.61 × 10− 3) ρg/site in the healthy group, 1.02 × 10− 3 (0.34 × 10− 3 – 2.75 × 10− 3) ρg/site in the mucositis group, and 0.47 × 10− 3 (0.26 × 10− 3 – 0.97 × 10− 3) ρg/site in the peri-implantitis group. Here, EDN1 is linked to mucositis.