Faot et al. [12] and Ghassib et al. [13] identified biomarkers such as Interleukin 1β (IL-1β), Tumor Necrosis Factor-alpha (TNF-α), and Matrix metalloproteinase 8 (MMP-8) in the peri-implant sulcus fluid (PISF) as valuable for diagnosing peri-implantitis [14, 15]. The gene discussed is IL1B; the disease is Peri-Implantitis.