Additionally, two factors were identified as risk factors for PCa: Glial cell line-derived neurotrophic factor (OR: 1.05, 95% CI: 1.01–1.11, P = 0.027) and SIR2-like protein 2 (OR: 1.07, 95% CI: 1.00–1.14, P = 0.038) (Figure 4). Here, SIRT2 is linked to posterior cortical atrophy.