ENO1 and cancer: Additionally, the permissive assembly of the PGK1‐PGAM1‐ENO1‐PKM2‐LDHA complex through gLINC has been shown to enhance glycolytic capacity.[25] Such complexes aid in “channeling” metabolites between consecutive enzymes, promoting catalytic efficiency and facilitating cancer cell growth.[26] This aligns with our proposition that Hsp90 forms multi‐enzyme complexes to promote glycolytic efficiency from a biochemical reaction perspective, thereby increasing intracellular glycolytic levels and generating abundant ATP and lactate.