When analyzed as a group, the 4 FTLD lines (Pick disease [PiD], progressive supranuclear palsy [PSP], corticobasal degeneration [CBD], and FTLD-Tau) did not show significantly different Aβ42/40 or Aβ43/40 ratios compared to controls (P = .117 and .54, respectively). The gene discussed is MAPT; the disease is progressive supranuclear palsy.