NPC2 and neoplasm: Preliminary evidence comparing the transcriptional signatures of macrophages in the SATB2 expressing tumor indicates that TIE:EGFP+ macrophages have higher expression of cholesterol and fatty acid genes (i.e. abca1a, npc2) as well as apoptotic genes (i.e. casp3b, caspa) compared to TIE:EGFP- macrophages.