TGFB1 and melanoma: Melanoma cells have increased expression and secretion of TGFb ligands compared to normal melanocytes, and TGFb ligand expression correlates with melanoma progression (Van Belle et al., 1996; Albino et al., 1991; Rodeck et al., 1991; Rodeck et al., 1994; Krasagakis et al., 1998; Javelaud et al., 2008; Perrot et al., 2013; Rak et al., 1996; Cerami et al., 2012; Gao et al., 2013; Lauden et al., 2014; Schmid et al., 1995).