In colorectal and urothelial cancers, TGFb in the tumor microenvironment was found to mediate immune evasion such that TGFb inhibition rendered these tumors susceptible to anti-PD-1/PD-L1 immune checkpoint inhibitors (Tauriello et al., 2018; Mariathasan et al., 2018). Here, TGFB1 is linked to neoplasm.