PTPRN belongs to the family of receptor‐type protein tyrosine phosphatases (RPTPs) and has been identified as a major autoantigen in type 1 diabetes.[13] While extensive research has elucidated its role in regulating insulin secretion and glucose homeostasis in pancreatic β‐cells,[14] the broad expression of PTPRN suggests that it may have wider functions.[15] In particular, the role of PTPRN in hippocampal granule cells remains poorly understood, making it an intriguing area for further investigation in the context of TLE. Here, PTPRN is linked to type 1 diabetes mellitus.