Consistent correlations between Cdh1 depletion and CENP‐A upregulation observed across human hepatocellular carcinoma cells (Hep G2), lung carcinoma cells (A549), triple‐negative breast cancer cells (MDA‐MB‐231), glioblastoma cells (U251), and normal liver cells (L‐02) suggested that Cdh1 is generally responsible for CENP‐A regulation in human cells (Figure S11, Supporting Information). Here, CENPA is linked to glioblastoma.