MIF and hyperthyroidism: The presence of interleukin-13 (IL-13) and macrophage migration inhibitory factor (MIF) are causally associated with hyperthyroidism (OR = 1.046, 95% CI: 1.008–1.086, p = 0.019; OR = 1.052, 95% CI: 1.007–1.099, p = 0.022, respectively) (Supplementary Figure S7, Supplementary Table 10 and Supplementary Table 11).