Therapeutic interventions with relatively large numbers of clinical applications include Bexarotene (Table 4), exosomes, PXR agonists, ketone bodies, N-methyl-D-aspartate receptor agonists [which would be contraindicated in AD, because excitotoxicity has been implicated in AD-associated neurotoxicity (Wang and Reddy, 2017)], Pirenzepine (Table 5), Oleocanthal/extra virgin olive oil (Tables 4, 5, 8), Dexamethasone (Tables 7, 9), intermittent hypoxia, Progesterone, Epidermal Growth Factor, and Doxorubicin (Table 9). The gene discussed is NR1I2; the disease is Alzheimer disease.