DEGs derived from the 4 CD8+ T cell sub‐populations observed above in ccRCC were subjected to a gene concept network analysis, CD8+ T cell (NCF1), CD8+ T cell (MT‐ND4), and CD8+ T cell (SPC25) were found to potentially contribute to ccRCC metastasis to Leukemia, Lymphoma, while CD8+ T cell (FGFBP2) appears to potentially contribute to ccRCC metastasis to Ki‐1+ Anaplastic Large Cell Lymphoma (Fig. 4A–D; Table S2). The gene discussed is TNFRSF8; the disease is leukemia.