In the literature review, rare variants in genes such as MAPT, GRN, C9orf72, CHCHD10, VCP, TBK1, OPTN, SQSTM1, SIGMAR1, TARDBP, UBQLN2, FUS, CCNF, and CYLD were identified in Chinese FTD populations [8, 28–36]. The gene discussed is CYLD; the disease is frontotemporal dementia.