Consistent with prior genetic studies on Chinese FTD patients [8, 35], our analysis revealed rare variants in MAPT, GRN, TBK1, PRNP, and the GGGGCC repeats in the C9orf72. Additionally, we observed rare variants in OPTN, ANXA11, CHMP2B, CYLD, SQSTM1, VCP, TARDBP, UBQLN2, CCNF, CHCHD10, SIGMAR1, CHCHD2, FUS, and TMEM106B. Here, SIGMAR1 is linked to frontotemporal dementia.