The optimal model included genes such as GGTLC1, SLPI, SFTPB, CXCL17, POLR2F, KRT18, CHCHD2, and GPRC5A. Immunohistochemical data demonstrated elevated expression levels of CHCHD2 in lung cancer tissues compared to normal tissues [70, 71]. This evidence concerns the gene KRT18 and lung carcinoma.