MCL1 and obesity due to melanocortin 4 receptor deficiency: There was an important association between features of the metabolic syndrome and EAT expression which might also lead to worse outcomes in severely injured trauma patients with a reported odds ratio of 1.75 (95% CI 1.39–2.19) for in-hospital mortality in a recent large meta-analysis investigating the prognostic relevance of obesity and metabolic syndrome [14, 15].