APP and amyloidosis: It is not surprising that the treatment of our mouse model of amyloidosis with Aβice did not result in any alterations of APP processing, since Aβice injected in the animal models is not the APPA673T (i.e., the substrate of the β-secretase activity) but Aβice (i.e., the post-processing Aβ fragment of APPA673T).