Figure 1 demonstrates that 36 studies met the inclusion criteria and were enrolled for analysis of the prognostic value of E-cad expression, as well as its association with clinical characteristics and risk factors for GC (of the 1985 publications, 1921 studies were excluded due to incomplete content, 16 were excluded because they lacked sufficient data to calculate OS, and 12 were excluded as their data overlapped with those of other studies). Here, CDH1 is linked to gastric cancer.