In horses, over 10 independent variants in the MITF (OMIA 000214-9796) and PAX3 (OMIA 001688-9796) genes explain the splashed white phenotype, frequently accompanied by blue eyes and, in some cases, deafness (Hauswirth et al. 2012, 2013; Dürig et al. 2017; Henkel et al. 2019; Magdesian et al. 2020; Patterson Rosa et al. 2022; Bellone et al. 2023; McFadden et al. 2023). This evidence concerns the gene PAX3 and deafness.