To verify the CD4+ naive T cell differentiation in MDD patients prior to or post‐antidepressant treatment, 35 antidepressant‐free MDD patients (19 responders and 16 nonresponders) and 40 HCs were enrolled for the flow cytology study (Figure 6; Figure S7, Table S4, Supporting Information). The gene discussed is CD4; the disease is major depressive disorder.