ST8SIA1 and pachyonychia congenita: This study did not examine the ganglioside products of GD3S, and reported high GD3S expression in all 4 PC cell lines examined; the latter is not confirmed by our analysis of the mRNA expression of the same cell lines reported in a comprehensive epigenetics/transcriptomics study26 and our analyses demonstrate little or no GD2 expression on some of these PC cell lines (See Results).