Previously, an elevated ferritin level, positivity for Hepatitis B Surface Antigen (HBsAg) or for antinuclear antibody (ANA), platelet counts ≥ 20 × 109/L and older age were identified as adverse factors for adult ITP relapse and response to treatment outcomes [18, 20, 21], while age > 6 yrs, higher platelet count at diagnosis and lower absolute lymphocyte count were identified as adverse risk factors in pediatric ITP outcomes [22, 23]. Here, BTG3 is linked to autoimmune thrombocytopenic purpura.