In the present study, we investigated cholinergic differences between PD patients and matched controls, and also between patients with and without VH, using the PET tracer (2R,3R)-5-(2-[18F]fluoroethoxy)benzovesamicol (18F-FEOBV), which binds to the vesicular acetylcholine transporter (VAChT). Here, SLC18A3 is linked to Parkinson disease.