For example, GRIN2A and SLC12A5 are associated with schizophrenia and bipolar disorder, respectively, by GWAS (p < 10−8) and are targets for psychoactive drugs (DA and ARA); both genes are also consistently upregulated in TL and dysregulated (upregulated) in brain tissue from schizophrenia patients (bold font, tables in figure 3c–e), which were confirmed by qPCR (our samples) as well as by independent analysis of Allen Brain Atlas data (electronic supplementary material, figure S12b,c). This evidence concerns the gene GRIN2A and bipolar disorder.