CD274 and neoplasm: The PD-L1 expression on tumoral cells was associated with lymphovascular invasion (LVI) and perineural invasion (PNI) with P- values of 0.012 and 0.005, respectively, while PD-L1 expression on TIICs was associated with tumor budding with a P-value of 0.022.<h4>Conclusion</h4>IHC expression of PD-L1 on tumoral cells and immune cells may be associated with some known poor prognostic factors.