STAT3 and colorectal carcinoma: Correlations between the H-score of pSTAT3 and CTLA4 in CRC showed a significant positive correlation (<i>P</i><0.001).<h4>Conclusion</h4>STAT3 and CTLA4 positivity may be linked to the development and progression of the CRC, and they may provide potential prognostic indicators and therapeutic targets for CRC patients.