There was a positive association between LRP1/6 expression and the infiltration of CD8+ T cells, CD4+ T Cell, Macrophage, Dendritic Cell, and Neutrophil.<h4>Conclusion</h4>Our study recommends LDLR as a potential prognostic biomarker that can be promising to improve the survival of BC patients' survival. The gene discussed is CD4; the disease is breast cancer.