CD63 and neoplasm: We wish to note that although we could non-specifically capture miRNA NGS profiles from the EBC of control mice using our anti-human anti-CD63 EV-CATCHER assay, these profiles only contained 10.5% of the detectable miRNAs with 1,000 times fewer miRNA reads compared to human tumor-derived EVs purified from the EBC of lung tumor-bearing mice.