Additionally, it is important to note that long term COVID-19/PASC symptoms are also related to associated inflicted organ/tissue injury (Del Rio et al., 2020); for example, the development of lung fibrosis and pulmonary fibrosis (that subsequently causes the deposition of extracellular matrix molecules such as fibronectin, collagen, and laminin in parenchymal lung tissues; hindering gas exchange in the lungs). Here, FN1 is linked to pulmonary fibrosis.